Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_1106Sindbis virusAR339RNATogaviridaeNoneYesNoNoATCCCervical cancer cell lineHeLaS31.0E+5 cells per wellNAFluoroscent mesure at 450nm0.01MOI50% cell viabilityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1107Sindbis virusAR339RNATogaviridaeNoneYesNoNoATCCCervical cancer cell lineHeLaS31.0E+5 cells per wellNAFluoroscent mesure at 450nm0.1MOI35% cell viabilityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1108Sindbis virusAR339RNATogaviridaeNoneYesNoNoATCCCervical cancer cell lineHeLaS31.0E+5 cells per wellNAFluoroscent mesure at 450nm1MOI15% cell viablityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1109Sindbis virusAR339RNATogaviridaeNoneYesNoNoATCCCervical cancer cell lineC33A1.0E+5 cells per wellNAFluoroscent mesure at 450nm0.01MOI70% cell viabilityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1110Sindbis virusAR339RNATogaviridaeNoneYesNoNoATCCCervical cancer cell lineC33A1.0E+5 cells per wellNAFluoroscent mesure at 450nm0.1MOI50% cell viabilityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1111Sindbis virusAR339RNATogaviridaeNoneYesNoNoATCCCervical cancer cell lineC33A1.0E+5 cells per wellNAFluoroscent mesure at 450nm1MOI35% cell viablityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1112Sindbis virusAR339RNATogaviridaeNoneYesNoNoHamamatsu university school of medicine, japanOvarian cancer cell lineHOC-11.0E+5 cells per wellNAFluoroscent mesure at 450nm0.01MOI90% cell viablityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1113Sindbis virusAR339RNATogaviridaeNoneYesNoNoHamamatsu university school of medicine, japanOvarian cancer cell lineHOC-11.0E+5 cells per wellNAFluoroscent mesure at 450nm0.1MOI80% cell viablityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1114Sindbis virusAR339RNATogaviridaeNoneYesNoNoHamamatsu university school of medicine, japanOvarian cancer cell lineHOC-11.0E+5 cells per wellNAFluoroscent mesure at 450nm1MOI60% cell viablityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1115Sindbis virusAR339RNATogaviridaeNoneYesNoNoTsukuba University, JapanOvarian cancer cell lineHAC-21.0E+5 cells per wellNAFluoroscent mesure at 450nm0.01MOI90% cell viablityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1116Sindbis virusAR339RNATogaviridaeNoneYesNoNoTsukuba University, JapanOvarian cancer cell lineHAC-21.0E+5 cells per wellNAFluoroscent mesure at 450nm0.1MOI60% cell viablityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1117Sindbis virusAR339RNATogaviridaeNoneYesNoNoTsukuba University, JapanOvarian cancer cell lineHAC-21.0E+5 cells per wellNAFluoroscent mesure at 450nm1MOI30% cell viablityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1118Sindbis virusAR339RNATogaviridaeNoneYesNoNoOsaka Medical college, japanOvarian cancer cell lineOMC-31.0E+5 cells per wellNAFluoroscent mesure at 450nm0.01MOI100% cell viablityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1119Sindbis virusAR339RNATogaviridaeNoneYesNoNoOsaka Medical college, japanOvarian cancer cell lineOMC-31.0E+5 cells per wellNAFluoroscent mesure at 450nm0.1MOI70% cell viabilityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1120Sindbis virusAR339RNATogaviridaeNoneYesNoNoOsaka Medical college, japanOvarian cancer cell lineOMC-31.0E+5 cells per wellNAFluoroscent mesure at 450nm1MOI70% cell viabilityNoNoNA No responseApoptosis induction in cancer cell linesNANA15958641
OV_1136Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c nude mice xenograft for HeLaS3 cell line1.0E+6 pfu NA Complete reduction in tumor volume after 30 daysIntratumoral injectionApoptosis induction in cancer cell linesNA15958641
OV_1137Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c nude mice xenograft for C33A cell line1.0E+6 pfu NA Complete reduction in tumor volume after 30 daysIntratumoral injectionApoptosis induction in cancer cell linesNA15958641
OV_1138Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c nude mice xenograft for C33A cell line1.0E+6 pfu NA Rediction in tumor volume to 200mm after 50 daysIntravenous injectionApoptosis induction in cancer cell linesNA15958641
OV_1597Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-31.0E+5 cells per wellNALuminiscence measurement0.01 MOI40% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1598Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-21.0E+5 cells per wellNALuminiscence measurement0.01 MOI20% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1599Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSCC-41.0E+5 cells per wellNALuminiscence measurement0.01 MOI60% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1600Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSAT1.0E+5 cells per wellNALuminiscence measurement0.01 MOI65% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1601Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineOK-921.0E+5 cells per wellNALuminiscence measurement0.01 MOI30% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1602Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineCa9-221.0E+5 cells per wellNALuminiscence measurement0.01 MOI40% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1603Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSKN-31.0E+5 cells per wellNALuminiscence measurement0.01 MOI40% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1604Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineKON1.0E+5 cells per wellNALuminiscence measurement0.01 MOI45% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1605Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineKOSC-21.0E+5 cells per wellNALuminiscence measurement0.01 MOI55% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1606Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSa-31.0E+5 cells per wellNALuminiscence measurement0.01 MOI30% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1607Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineH-11.0E+5 cells per wellNALuminiscence measurement0.01 MOI30% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1608Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHO-1-N11.0E+5 cells per wellNALuminiscence measurement0.01 MOI50% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1609Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-41.0E+5 cells per wellNALuminiscence measurement0.01 MOI90% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1610Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-31.0E+5 cells per wellNALuminiscence measurement0.01 MOI40% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1611Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-21.0E+5 cells per wellNALuminiscence measurement0.01 MOI10% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1612Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSCC-41.0E+5 cells per wellNALuminiscence measurement0.01 MOI45% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1613Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSAT1.0E+5 cells per wellNALuminiscence measurement0.01 MOI20% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1614Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineOK-921.0E+5 cells per wellNALuminiscence measurement0.01 MOI30% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1615Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineCa9-221.0E+5 cells per wellNALuminiscence measurement0.01 MOI30% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1616Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSKN-31.0E+5 cells per wellNALuminiscence measurement0.01 MOI20% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1617Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineKON1.0E+5 cells per wellNALuminiscence measurement0.01 MOI25% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1618Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineKOSC-21.0E+5 cells per wellNALuminiscence measurement0.01 MOI35% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1619Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSa-31.0E+5 cells per wellNALuminiscence measurement0.01 MOI25% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1620Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineH-11.0E+5 cells per wellNALuminiscence measurement0.01 MOI25% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1621Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHO-1-N11.0E+5 cells per wellNALuminiscence measurement0.01 MOI35% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1622Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-41.0E+5 cells per wellNALuminiscence measurement0.01 MOI90% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1623Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-31.0E+5 cells per wellNALuminiscence measurement1 MOI30% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1624Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-21.0E+5 cells per wellNALuminiscence measurement1 MOI2% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1625Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSCC-41.0E+5 cells per wellNALuminiscence measurement1 MOI35% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1626Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSAT1.0E+5 cells per wellNALuminiscence measurement1 MOI15% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1627Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineOK-921.0E+5 cells per wellNALuminiscence measurement1 MOI20% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1628Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineCa9-221.0E+5 cells per wellNALuminiscence measurement1 MOI30% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1629Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSKN-31.0E+5 cells per wellNALuminiscence measurement1 MOI20% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1630Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineKON1.0E+5 cells per wellNALuminiscence measurement1 MOI20% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1631Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineKOSC-21.0E+5 cells per wellNALuminiscence measurement1 MOI30% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1632Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSa-31.0E+5 cells per wellNALuminiscence measurement1 MOI15% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1633Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineH-11.0E+5 cells per wellNALuminiscence measurement1 MOI25% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1634Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHO-1-N11.0E+5 cells per wellNALuminiscence measurement1 MOI20% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1635Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-41.0E+5 cells per wellNALuminiscence measurement1 MOI70% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1636Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-31.0E+5 cells per wellNALuminiscence measurement20 MOI100% cell death after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1637Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-21.0E+5 cells per wellNALuminiscence measurement20 MOI5% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1638Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSCC-41.0E+5 cells per wellNALuminiscence measurement20 MOI2% dells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1639Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSAT1.0E+5 cells per wellNALuminiscence measurement20 MOI3% dells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1640Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineOK-921.0E+5 cells per wellNALuminiscence measurement20 MOI7% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1641Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineCa9-221.0E+5 cells per wellNALuminiscence measurement20 MOI5% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1642Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSKN-31.0E+5 cells per wellNALuminiscence measurement20 MOI10% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1643Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineKON1.0E+5 cells per wellNALuminiscence measurement20 MOI30% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1644Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineKOSC-21.0E+5 cells per wellNALuminiscence measurement20 MOI2% dells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1645Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineSa-31.0E+5 cells per wellNALuminiscence measurement20 MOI20% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1646Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineH-11.0E+5 cells per wellNALuminiscence measurement20 MOI15% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1647Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHO-1-N11.0E+5 cells per wellNALuminiscence measurement20 MOI5% cells are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_1648Sindbis virusAR339RNAHantaviridaeNoneYesNoNoHuman Science Research Resource Bank, JapanOral squamous cell lineHSC-41.0E+5 cells per wellNALuminiscence measurement20 MOI60% cell are viable after 96 hoursNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANA19638980
OV_4205Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineSK-N-SH1.0E+5 cells per wellNALuminiscence measurement1 MOI1 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4206Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineIMR-321.0E+5 cells per wellNALuminiscence measurement1 MOI3 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4207Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineGOTO1.0E+5 cells per wellNALuminiscence measurement1 MOI5 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4208Sindbis virusAR339RNATogaviridaeNoneYesNoNoDr. R.C. Seeger, LAHuman neuroblastoma cell lineLan-51.0E+5 cells per wellNALuminiscence measurement1 MOI8 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathMaximum increased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4209Sindbis virusAR339RNATogaviridaeNoneYesNoNoDr. T. Sugimoto, JapanHuman neuroblastoma cell lineRT-BM-11.0E+5 cells per wellNALuminiscence measurement1 MOI8 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4210Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineSK-N-SH1.0E+5 cells per wellNALuminiscence measurement0.01 MOI1 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4211Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineSK-N-SH1.0E+5 cells per wellNALuminiscence measurement0.1 MOI1 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4212Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineSK-N-SH1.0E+5 cells per wellNALuminiscence measurement1 MOI1 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4213Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineIMR-321.0E+5 cells per wellNALuminiscence measurement0.01 MOI2 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4214Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineIMR-321.0E+5 cells per wellNALuminiscence measurement0.1 MOI2 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4215Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineIMR-321.0E+5 cells per wellNALuminiscence measurement1 MOI2 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4216Sindbis virusAR339RNATogaviridaeNoneYesNoNoDr. R.C. Seeger, LAHuman neuroblastoma cell lineLan-51.0E+5 cells per wellNALuminiscence measurement0.01 MOI10 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathMaximum increased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4217Sindbis virusAR339RNATogaviridaeNoneYesNoNoDr. R.C. Seeger, LAHuman neuroblastoma cell lineLan-51.0E+5 cells per wellNALuminiscence measurement0.1 MOI7 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathMaximum increased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4218Sindbis virusAR339RNATogaviridaeNoneYesNoNoDr. R.C. Seeger, LAHuman neuroblastoma cell lineLan-51.0E+5 cells per wellNALuminiscence measurement1 MOI6 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathMaximum increased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4219Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineGOTO1.0E+5 cells per wellNALuminiscence measurement0.01 MOI2 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4220Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineGOTO1.0E+5 cells per wellNALuminiscence measurement0.1 MOI2 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4221Sindbis virusAR339RNATogaviridaeNoneYesNoNoJapanese cancer research resource bankHuman neuroblastoma cell lineGOTO1.0E+5 cells per wellNALuminiscence measurement1 MOI2 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4222Sindbis virusAR339RNATogaviridaeNoneYesNoNoDr. T. Sugimoto, JapanHuman neuroblastoma cell lineRT-BM-11.0E+5 cells per wellNALuminiscence measurement0.01 MOI20 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4223Sindbis virusAR339RNATogaviridaeNoneYesNoNoDr. T. Sugimoto, JapanHuman neuroblastoma cell lineRT-BM-11.0E+5 cells per wellNALuminiscence measurement0.1 MOI10 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4224Sindbis virusAR339RNATogaviridaeNoneYesNoNoDr. T. Sugimoto, JapanHuman neuroblastoma cell lineRT-BM-11.0E+5 cells per wellNALuminiscence measurement1 MOI5 % cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4225Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)1.0E+6 pfuNA Complete reduction in tumor volume after 21 days in mice 1 and increase in PFS above 200 days compared to control 75 daysIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4226Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)1.0E+6 pfuNA Complete reduction in tumor volume after 42 days in mice 2 and increase in PFS above 200 days compared to control 75 daysIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4227Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)1.0E+6 pfuNA Complete reduction in tumor volume after 49 days in mice 3 and increase in PFS above 200 days compared to control 75 daysIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4228Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)1.0E+6 pfuNA Complete reduction in tumor volume after 56 days in mice 4 and increase in PFS above 200 days compared to control 75 daysIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4229Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)1.0E+6 pfuNA Reduction in tumor volume to 100 cubic millimetet after 70 days in mice 1 and increase in PFS above 200 days from 150 days to controlIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4230Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)1.0E+6 pfuNA Complete reduction in tumor volume after 49 days in mice 2 and increase in PFS above 200 days from 150 days to controlIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4231Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)1.0E+6 pfuNA Complete reduction in tumor volume after 49 days in mice 3 and increase in PFS above 200 days from 150 days to controlIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4232Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)1.0E+6 pfuNA Complete reduction in tumor volume after 56 days in mice 4 and increase in PFS above 200 days from 150 days to controlIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4233Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)1.0E+6 pfuNA Complete reduction in tumor volume after 56 days in mice 5 and increase in PFS above 200 days from 150 days to controlIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056
OV_4234Sindbis virusAR339RNATogaviridaeNoneYesNoNoNANANANANANANANABALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)1.0E+6 pfuNA Complete reduction in tumor volume after 70 days in mice 6 and increase in PFS above 200 days from 150 days to controlIntratumoralVirus induce apoptosis process leads to cancer cell deathIncreased expression of Bcl-2 and Bcl-xL expressionNA26298056